On this article, we compute a number of distance-based topological indices dendrimers. Certainly, based mostly on the distances of associated graphs, we examine the distance-based complexity of those graphs. We additionally, decide an orbit entropy measure of those buildings based mostly on the scale of orbits. The evaluation outcomes obtained by computing the correlations between given numerical information reveals that the correlation between Winer complexity with GP-index, Wiener index, and Wiener polarity is kind of low. Because of this, we’ve inferred that the Wiener-complexity may be thought of as new measures for quantitative structure-activity relationship/quantitative structure-property relationship (QSAR/QSPR) fashions of dendrimers. Therefore, the W-complexity could be fascinating for additional investigations in predicting the physicochemical properties of molecules.